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FREON 12

Filter By

Current Database

  • EMDB [12]

Current status

  • REL [12]

Sample type

  • Complex [12]
  • Protein [12]
  • Ligand [8]

Organism

  • Homo sapiens [9]
  • Danio rerio [3]
  • Spodoptera aff. frugiperda 1 bold-2017 [1]

EM Method

  • Single-particle [12]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [8]

Model molecular weight

  • 100-250 kDa [12]

Release Date

  • 2025 [1]
  • 2024 [11]

Author by name

  • Cai BY [12]
  • Huang S [12]
  • Huang SM [12]
  • Huang ZZ [12]
  • Li Z [12]
  • Liu L [12]
  • Sun J [12]
  • Sun JP [12]
  • Sun Y [12]
  • Xiong MY [12]
  • Yang BX [12]
  • Zhang C [12]
  • Zhang H [12]
  • Cai K [11]
  • Jia YL [11]
  • Li M [11]
  • Tie L [11]
  • Wang JL [11]
  • Wang MW [11]
  • Wen X [11]
  • Weng CH [11]
  • Xiao P [11]
  • Xie YH [11]
  • Yang F [11]
  • Yang Z [11]
  • Yi F [11]
  • Yu X [11]
  • Zhang MH [11]
  • Li YR [1]
  • Yang LJ [1]
  • Zhizheng H [1]

Author by ORCID

  • Liu L [12]
  • Yi F [11]
  • Jia YL [11]
  • Xiao P [11]
  • Yu X [11]
  • Sun JP [11]
  • Zhang H [11]

Journal

  • NAT COMMUN [11]
  • ACTA PHARMACOL.SIN. [1]

Microscope

  • FEI TITAN KRIOS [11]
  • FEI POLARA 300 [1]

Electron Source

  • OTHER [12]

Film or detector model

  • FEI FALCON II 4K X 4K [12]

External links

  • AlphaFold DB [12]
  • PDB [12]
  • UniProt [12]
  • PDBe-Kb [8]
  • Pfam [8]
  • Gene Ontology [7]
  • InterPro [7]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [2]
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EMD-63105
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3D View
Cryo-EM structure of inhibitor E3 bound human urea transporter A2.
Release date: Aug. 13, 2025
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 9lht
Q-score: 0.547

Huang SM, Cai BY, Liu L, Yang LJ, Li Z, Zhang C, Xiong MY, Zhang H, Li YR, Huang ZZ, Sun Y, Yang BX, Sun JP

Acta Pharmacol.Sin. (2025) 46 pp. 2989-2997 [ Pubmed: 40523902 DOI: doi:10.1038/s41401-025-01595-7 ]

EMD-38268
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Cryo-EM structure of inhibitor 25a bound human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xd7
Q-score: 0.461

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38270
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3D View
Cryo-EM structure of human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8xd9
Q-score: 0.547

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38271
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3D View
Cryo-EM structure of urea bound human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xda
Q-score: 0.54

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38272
Download Map
3D View
Cryo-EM structure of human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8xdb
Q-score: 0.515

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38273
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3D View
Cryo-EM structure of human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xdc
Q-score: 0.562

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38274
Download Map
3D View
Cryo-EM structure of human urea transporter A2.
Release date: Dec. 4, 2024
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8xdd
Q-score: 0.524

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38275
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3D View
Cryo-EM structure of human urea transporter A3.
Release date: Dec. 4, 2024
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 8xde
Q-score: 0.638

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38276
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3D View
Cryo-EM structure of human urea transporter B.
Release date: Dec. 4, 2024
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8xdf
Q-score: 0.654

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

EMD-38277
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3D View
Cryo-EM structure of zebrafish urea transporter.
Release date: Dec. 4, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8xdg
Q-score: 0.542

Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP

Nat Commun (2024) 15 pp. 10226-10226 [ DOI: doi:10.1038/s41467-024-54305-y Pubmed: 39587082 ]

Sort by: Download
Showing 1 - 10 of 12. Page 1 of 2
Display:
Statistics
×

Download










































Preview first 10
Download

Filter By

Current Database

  • EMDB [12]

Current status

  • REL [12]

Sample type

  • Complex [12]
  • Protein [12]
  • Ligand [8]

Organism

  • Homo sapiens [9]
  • Danio rerio [3]
  • Spodoptera aff. frugiperda 1 bold-2017 [1]

EM Method

  • Single-particle [12]

Resolution

  • ≥ 2Å and < 3Å [4]
  • ≥ 3Å and < 4Å [8]

Model molecular weight

  • 100-250 kDa [12]

Release Date

  • 2025 [1]
  • 2024 [11]

Author by name

  • Cai BY [12]
  • Huang S [12]
  • Huang SM [12]
  • Huang ZZ [12]
  • Li Z [12]
  • Liu L [12]
  • Sun J [12]
  • Sun JP [12]
  • Sun Y [12]
  • Xiong MY [12]
  • Yang BX [12]
  • Zhang C [12]
  • Zhang H [12]
  • Cai K [11]
  • Jia YL [11]
  • Li M [11]
  • Tie L [11]
  • Wang JL [11]
  • Wang MW [11]
  • Wen X [11]
  • Weng CH [11]
  • Xiao P [11]
  • Xie YH [11]
  • Yang F [11]
  • Yang Z [11]
  • Yi F [11]
  • Yu X [11]
  • Zhang MH [11]
  • Li YR [1]
  • Yang LJ [1]
  • Zhizheng H [1]

Author by ORCID

  • Liu L [12]
  • Yi F [11]
  • Jia YL [11]
  • Xiao P [11]
  • Yu X [11]
  • Sun JP [11]
  • Zhang H [11]

Journal

  • NAT COMMUN [11]
  • ACTA PHARMACOL.SIN. [1]

Microscope

  • FEI TITAN KRIOS [11]
  • FEI POLARA 300 [1]

Electron Source

  • OTHER [12]

Film or detector model

  • FEI FALCON II 4K X 4K [12]

External links

  • AlphaFold DB [12]
  • PDB [12]
  • UniProt [12]
  • PDBe-Kb [8]
  • Pfam [8]
  • Gene Ontology [7]
  • InterPro [7]
  • ChEBI [3]
  • ChEMBL [3]
  • DrugBank [2]