EMD-45005

Helical reconstruction
2.7 Å
EMD-45005
3D View Gallery
Deposition: 22/05/2024
Map released: 14/08/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45005

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9bxi summary report (pdf.gz) Map-9bxi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Paired Helical Filament of tau amyloids found in Down Syndrome individuals

EMD-45005

Helical reconstruction
2.7 Å
EMD-45005
3D View Gallery
Deposition: 22/05/2024
Map released: 14/08/2024
Last modified: 14/08/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Paired Helical Filaments purified from Down Syndrome individual brain tissue
Fitted models: 9bxi

Deposition Authors: Tse E, Ghosh U, Condello C , Southworth D
Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Ghosh U, Tse E, Yang H , Shi M, Caro CD, Wang F, Merz GE, Prusiner SB, Southworth DR, Condello C
(2024) Acta Neuropathol , 12 , 94 - 94
PUBMED: 38867338
DOI: doi:10.1186/s40478-024-01806-y
ISSN: 2051-5960