EMD-43799

Single-particle
3.37 Å
EMD-43799
3D View Gallery
Deposition: 24/02/2024
Map released: 02/04/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43799

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9arz summary report (pdf.gz) Map-9arz FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Local refinement of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)

EMD-43799

Single-particle
3.37 Å
EMD-43799
3D View Gallery
Deposition: 24/02/2024
Map released: 02/04/2025
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 5-HT2AR in complex with mini-Gq
Fitted models: 9arz

Deposition Authors: Gumpper RH , Fay JF , Roth BL
The structural diversity of psychedelic drug actions revealed.
Gumpper RH , Jain MK , Kim K, Sun R, Sun N, Xu Z, DiBerto JF, Krumm BE , Kapolka NJ, Kaniskan HU , Nichols DE, Jin J , Fay JF , Roth BL
(2025) Nat Commun , 16 , 2734 - 2734
PUBMED: 40108183
DOI: doi:10.1038/s41467-025-57956-7
ISSN: 2041-1723