EMD-17726

Helical reconstruction
3.3 Å
EMD-17726
3D View Gallery
Deposition: 24/06/2023
Map released: 29/05/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-17726

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8pk4 summary report (pdf.gz) Map-8pk4 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo EM structure of the type 5A polymorph of alpha-synuclein.

EMD-17726

Helical reconstruction
3.3 Å
EMD-17726
3D View Gallery
Deposition: 24/06/2023
Map released: 29/05/2024
Last modified: 11/09/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: alpha-synuclein amyloid fibril
Fitted models: 8pk4

Deposition Authors: Frey L, Qureshi BM, Kwiatkowski W, Rhyner D, Greenwald J , Riek R
On the pH-dependence of alpha-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation.
Frey L, Ghosh D, Qureshi BM, Rhyner D, Guerrero-Ferreira R, Pokharna A , Kwiatkowski W, Serdiuk T, Picotti P , Riek R, Greenwald J
(2024) eLife , 12
PUBMED: 39196271
DOI: doi:10.7554/eLife.93562
ISSN: 2050-084X
Grant Support: