EMD-9376
B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
EMD-9376
Single-particle3.8 Å
Deposition: 26/12/2018Map released: 20/11/2019
Last modified: 16/10/2024
Sample Organism:
Homo sapiens,
Lama glama
Sample: B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Fitted models: 6ni3
Deposition Authors: Nguyen AH
,
Thomsen ARB
Sample: B2V2R-Gs protein subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Fitted models: 6ni3
Deposition Authors: Nguyen AH
,
Thomsen ARB
Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nguyen AH ,
Thomsen ARB ,
Cahill 3rd TJ,
Huang R,
Huang LY,
Marcink T ,
Clarke OB,
Heissel S,
Masoudi A,
Ben-Hail D ,
Samaan F ,
Dandey VP,
Tan YZ ,
Hong C,
Mahoney JP ,
Triest S ,
Little 4th J ,
Chen X ,
Sunahara R ,
Steyaert J ,
Molina H,
Yu Z,
des Georges A ,
Lefkowitz RJ
(2019) Nat Struct Mol Biol , 26 , 1123 - 1131
,
Thomsen ARB ,
Cahill 3rd TJ,
Huang R,
Huang LY,
Marcink T ,
Clarke OB,
Heissel S,
Masoudi A,
Ben-Hail D ,
Samaan F ,
Dandey VP,
Tan YZ ,
Hong C,
Mahoney JP ,
Triest S ,
Little 4th J ,
Chen X ,
Sunahara R ,
Steyaert J ,
Molina H,
Yu Z,
des Georges A ,
Lefkowitz RJ
(2019) Nat Struct Mol Biol , 26 , 1123 - 1131
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): 2R01-HL016037-47 (United States)