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EMD-9375
Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
EMD-9375
Single-particle4.0 Å
Deposition: 26/12/2018Map released: 20/11/2019
Last modified: 20/11/2024
Sample Organism:
synthetic construct,
Lama glama,
Bos taurus,
Homo sapiens
Sample: Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Fitted models: 6ni2
Deposition Authors: Nguyen AH
,
Thomsen ARB
Sample: Stabilized beta-arrestin 1-V2T subcomplex of a GPCR-G protein-beta-arrestin mega-complex
Fitted models: 6ni2
Deposition Authors: Nguyen AH
,
Thomsen ARB
Structure of an endosomal signaling GPCR-G protein-beta-arrestin megacomplex.
Nguyen AH ,
Thomsen ARB ,
Cahill 3rd TJ,
Huang R,
Huang LY,
Marcink T ,
Clarke OB,
Heissel S,
Masoudi A,
Ben-Hail D ,
Samaan F ,
Dandey VP,
Tan YZ ,
Hong C,
Mahoney JP ,
Triest S ,
Little 4th J ,
Chen X ,
Sunahara R ,
Steyaert J ,
Molina H,
Yu Z,
des Georges A ,
Lefkowitz RJ
(2019) Nat Struct Mol Biol , 26 , 1123 - 1131
,
Thomsen ARB ,
Cahill 3rd TJ,
Huang R,
Huang LY,
Marcink T ,
Clarke OB,
Heissel S,
Masoudi A,
Ben-Hail D ,
Samaan F ,
Dandey VP,
Tan YZ ,
Hong C,
Mahoney JP ,
Triest S ,
Little 4th J ,
Chen X ,
Sunahara R ,
Steyaert J ,
Molina H,
Yu Z,
des Georges A ,
Lefkowitz RJ
(2019) Nat Struct Mol Biol , 26 , 1123 - 1131
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)
- National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI): 2R01-HL016037-47 (United States)