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EMD-8943

Single-particle
3.6 Å
EMD-8943
3D View Gallery
Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8943
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6dzz summary report (pdf.gz) Map and 6dzz FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM Structure of the wild-type human serotonin transporter in complex with ibogaine and 15B8 Fab in the inward conformation

EMD-8943

Single-particle
3.6 Å
EMD-8943
3D View Gallery
Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Human serotonin transporter in complex with Fab bound to ibogaine
Fitted models: 6dzz

Deposition Authors: Yang D, Coleman JA
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Coleman JA, Yang D, Zhao Z , Wen PC , Yoshioka C, Tajkhorshid E, Gouaux E
(2019) Nature , 569 , 141 - 145
PUBMED: 31019304
DOI: doi:10.1038/s41586-019-1135-1
ISSN: 1476-4687
ASTM: NATUAS