EMD-8942

Single-particle
4.1 Å
EMD-8942 Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8942

Cryo-EM structure of the ts2-active human serotonin transporter in complex with 15B8 Fab and 8B6 ScFv bound to ibogaine

EMD-8942

Single-particle
4.1 Å
EMD-8942 Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Human serotonin transporter in complex with Fab/Fv bound to ibogaine
Fitted models: 6dzy

Deposition Authors: Coleman JA, Yang D
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Coleman JA, Yang D, Zhao Z , Wen PC , Yoshioka C, Tajkhorshid E, Gouaux E
(2019) Nature , 569 , 141 - 145
PUBMED: 31019304
DOI: doi:10.1038/s41586-019-1135-1
ISSN: 1476-4687
ASTM: NATUAS