Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-8941

Single-particle
4.3 Å
EMD-8941 Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8941

Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv

EMD-8941

Single-particle
4.3 Å
EMD-8941 Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Human serotonin transporter in complex with Fab/Fv bound to paroxetine
Fitted models: 6dzw

Deposition Authors: Coleman JA, Yang D
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Coleman JA, Yang D, Zhao Z , Wen PC , Yoshioka C, Tajkhorshid E, Gouaux E
(2019) Nature , 569 , 141 - 145
PUBMED: 31019304
DOI: doi:10.1038/s41586-019-1135-1
ISSN: 1476-4687
ASTM: NATUAS