EMD-8941

Single-particle
4.3 Å
EMD-8941
3D View Gallery
Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8941

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6dzw summary report (pdf.gz) Map-6dzw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv

EMD-8941

Single-particle
4.3 Å
EMD-8941
3D View Gallery
Deposition: 05/07/2018
Map released: 24/04/2019
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Human serotonin transporter in complex with Fab/Fv bound to paroxetine
Fitted models: 6dzw

Deposition Authors: Coleman JA, Yang D
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Coleman JA, Yang D, Zhao Z , Wen PC , Yoshioka C, Tajkhorshid E, Gouaux E
(2019) Nature , 569 , 141 - 145
PUBMED: 31019304
DOI: doi:10.1038/s41586-019-1135-1
ISSN: 1476-4687
ASTM: NATUAS