Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-8882

Single-particle
3.75 Å
EMD-8882
3D View Gallery
Deposition: 07/08/2017
Map released: 18/10/2017
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8882
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 5wpt summary report (pdf.gz) Map and 5wpt FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution

EMD-8882

Single-particle
3.75 Å
EMD-8882
3D View Gallery
Deposition: 07/08/2017
Map released: 18/10/2017
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Homotetramer of mouse TRPML1
Fitted models: 5wpt

Deposition Authors: Chen Q, She J
Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.
Chen Q, She J, Zeng W, Guo J , Xu H, Bai XC, Jiang Y
(2017) Nature , 550 , 415 - 418
PUBMED: 29019981
DOI: doi:10.1038/nature24035
ISSN: 0028-0836
ASTM: NATUAS