EMD-8576

Single-particle
3.2 Å
EMD-8576
3D View Gallery
Deposition: 27/01/2017
Map released: 01/03/2017
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8576

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-5umd summary report (pdf.gz) Map-5umd FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the Plasmodium falciparum 80S ribosome bound to the antimalarial drug mefloquine

EMD-8576

Single-particle
3.2 Å
EMD-8576
3D View Gallery
Deposition: 27/01/2017
Map released: 01/03/2017
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Plasmodium falciparum 3D7
Sample: Plasmodium falciparum 80S ribosome bound to mefloquine
Fitted models: 5umd

Deposition Authors: Wong W , Bai X-C
Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Wong W , Bai XC, Sleebs BE , Triglia T, Brown A , Thompson JK, Jackson KE, Hanssen E , Marapana DS, Fernandez IS , Ralph SA , Cowman AF , Scheres SH, Baum J
(2017) Nat Microbiol , 2 , 17031 - 17031
PUBMED: 28288098
DOI: doi:10.1038/nmicrobiol.2017.31
ISSN: 2058-5276