EMDB < EMD-83886

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

EMD-83886

Tomography

EMD-83886

Gallery

Deposition: 29/09/2026
Map released: 28/10/2026
Last modified: 28/10/2026

Overview Sample Experiment Validation Additional data Links

Overview 3D View Sample Experiment Validation Additional data Links

EMD-83886

Cryo-electron tomogram of endolysosomes in LLOMe-treated U2OS cells, tomogram 1

EMD-83886

Tomography
EMD-83886

EMD-83886

Gallery

Deposition: 29/09/2026
Map released: 28/10/2026
Last modified: 28/10/2026

Overview Sample Experiment Validation Additional data Links

Sample Organism: Homo sapiens
Sample: LLOMe-treated U2OS cell

Deposition Authors: Zhang Y, Ni T, Li X, Jiang HB

Endolysosomal damage promotes intraluminal protein condensate formation that limits cytosolic leakage

Li X, Zhang Y, Zhao KQ, Chen G, Cui D, Nikan M, Young SG, Li XY, Bennett CF, Seth PP, Ni T, Gutierrez MG, Jiang HB
To Be Published

Grant Support:

The University Grants Committee, Research Grants Council (RGC): 17102722 (Hong Kong)
The University Grants Committee, Research Grants Council (RGC): 17300523 (Hong Kong)
The University Grants Committee, Research Grants Council (RGC): 17302324 (Hong Kong)