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EMD-8169
cryo-EM map of the full-length human NPC1 in complex with the cleaved glycoprotein of Ebola virus
EMD-8169
Single-particle6.56 Å
Deposition: 01/05/2016Map released: 08/06/2016
Last modified: 05/08/2020
Sample Organism:
Homo sapiens
Sample: NPC1 in complex with EBOV-GPcl trimer
Fitted models: 5jnx
Deposition Authors: Yan N, Zhou Q, Gong X, Qiang HW, Zhou XH, Wu JP, Gao F, Wan T, Shi Y
Sample: NPC1 in complex with EBOV-GPcl trimer
Fitted models: 5jnx
Deposition Authors: Yan N, Zhou Q, Gong X, Qiang HW, Zhou XH, Wu JP, Gao F, Wan T, Shi Y
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
Gong X 
,
Qian H,
Zhou X,
Wu J,
Wan T ,
Cao P,
Huang W,
Zhao X,
Wang X,
Wang P,
Shi Y,
Gao GF,
Zhou Q,
Yan N
(2016) Cell , 165 , 1467 - 1478
,
Qian H,
Zhou X,
Wu J,
Wan T ,
Cao P,
Huang W,
Zhao X,
Wang X,
Wang P,
Shi Y,
Gao GF,
Zhou Q,
Yan N
(2016) Cell , 165 , 1467 - 1478
Grant Support:
- Ministry of Science and Technology of China: 2015CB9101012014 (China)
- National Natural Science Foundation of China: 31321062 (China)
- Ministry of Science and Technology of China: ZX09507003006 (China)
- special project of Ebola virus research from the President Foundation of Chinese Academy of Sciences and Strategic Priority Research Program of the Chinese Academy of Sciences: XDB08020100 (China)
- National Natural Science Foundation of China: 81590761 (China)