EMD-8080

Single-particle
19.0 Å
EMD-8080 Deposition: 20/02/2016
Map released: 23/03/2016
Last modified: 14/02/2018
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-8080

B41 SOSIP.664 HIV-1 Env trimer in complex with anti-HIV CH235.9 wk152 Fab

EMD-8080

Single-particle
19.0 Å
EMD-8080 Deposition: 20/02/2016
Map released: 23/03/2016
Last modified: 14/02/2018
Overview 3D View Sample Experiment Validation Additional data Links
Name: Complex containing 3 copies of CH235.9 wk152 anti-HIV Fab bound to a trimer of HIV-1 Env B41 SOSIP.664
Complex [3]
Name: Complex containing 3 copies of CH235.9 wk152 anti-HIV Fab bound to a trimer of HIV-1 Env B41 SOSIP.664
Molecular weight
Experimental Theoretical Method
- 420 kDa -
Name: HIV-1 Env B41 SOSIP.664
Details: Solubilized and stabilized HIV-1 Env trimer from strain B41. Engineered disulfide between A501C and T605C. I559P mutation to stabilize in pre-fusion state. Truncation after D664 to increase solubility. Formed with three gp140 subunits.
Natural source [1]
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - HEK293F pPPI4
Name: Anti-HIV CH235.9 wk152 antibody fragment antigen binding
Natural source [1]
Organism: Homo sapiens
Recombinant Expression [1]
Organism Strain Cell Plasmid
Homo sapiens - Expi 293 pcDNA3.1
Molecular weight
Experimental Theoretical Method
- 50 kDa -