EMD-8080
B41 SOSIP.664 HIV-1 Env trimer in complex with anti-HIV CH235.9 wk152 Fab
EMD-8080
Single-particle19.0 Å
Deposition: 20/02/2016Map released: 23/03/2016
Last modified: 14/02/2018
Name: Complex containing 3 copies of CH235.9 wk152 anti-HIV Fab bound to a trimer of HIV-1 Env B41 SOSIP.664
Summary:
Name: Complex containing 3 copies of CH235.9 wk152 anti-HIV Fab bound to a trimer of HIV-1 Env B41 SOSIP.664
Molecular weight
| Experimental | Theoretical | Method |
|---|---|---|
| - | 420 kDa | - |
Name: HIV-1 Env B41 SOSIP.664
Details: Solubilized and stabilized HIV-1 Env trimer from strain B41. Engineered disulfide between A501C and T605C. I559P mutation to stabilize in pre-fusion state. Truncation after D664 to increase solubility. Formed with three gp140 subunits.
Details: Solubilized and stabilized HIV-1 Env trimer from strain B41. Engineered disulfide between A501C and T605C. I559P mutation to stabilize in pre-fusion state. Truncation after D664 to increase solubility. Formed with three gp140 subunits.
Natural source [1]
Recombinant Expression [1]
| Organism | Strain | Cell | Plasmid |
|---|---|---|---|
| Homo sapiens | - | HEK293F | pPPI4 |
Name: Anti-HIV CH235.9 wk152 antibody fragment antigen binding
Natural source [1]
Organism: Homo sapiens
Recombinant Expression [1]
| Organism | Strain | Cell | Plasmid |
|---|---|---|---|
| Homo sapiens | - | Expi 293 | pcDNA3.1 |
Molecular weight
| Experimental | Theoretical | Method |
|---|---|---|
| - | 50 kDa | - |
