EMD-80448

Single-particle
2.67 Å
EMD-80448
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-80448

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-25xm summary report (pdf.gz) Map-25xm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the Crimean-Congo hemorrhagic fever virus L protein (5'-cRNA-bound form)

EMD-80448

Single-particle
2.67 Å
EMD-80448
3D View Gallery
Deposition: 22/04/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Orthonairovirus haemorrhagiae, synthetic construct
Sample: the Crimean-Congo hemorrhagic fever virus L protein in complex with a 14-nt 5'-cRNA
Fitted models: 25xm

Deposition Authors: Jia H, Liu S, Gong P
RNA synthesis and substrate analog inhibition in the CCHFV polymerase
Jia H, Tang B, Liu S, Wen X, Wu F, Hu X, Zhou H, Chong T, Lv L, Liu Q, Rao G, Wei M, Jing X, Cao S, Deng F, Hu Z, Shu B, Gong R, Wu J, Wang M, Gong P
(2026) Nature
DOI: doi:10.1038/s41586-026-10913-w
ISSN: 1476-4687
ASTM: NATUAS