EMD-78693

Single-particle
5.9 Å
EMD-78693
3D View Gallery
Deposition: 18/08/2026
Map released: 23/09/2026
Last modified: 23/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-78693

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Local refinement of agonist-bound mGluR8 CRD and TMD in complex to G protein heterotrimer

EMD-78693

Single-particle
5.9 Å
EMD-78693
3D View Gallery
Deposition: 18/08/2026
Map released: 23/09/2026
Last modified: 23/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: Metabotropic Glutamate receptor bound to G proteins alpha i-1, beta-1, and gamma-2 in the presence of agonist and PAM and scFv14

Deposition Authors: Marx DC, Levitz JT
Structural basis of active state coupling of metabotropic glutamate receptor 8 to beta-arrestins.
Marx DC, Huynh K, Gonzalez-Hernandez AJ, Strauss A, Rico C, Gallo PN, Sharghi Moshtaghin S, Arefin A, Broichhagen J, Eliezer D, Khelashvili G, Levitz J
(2026) Nat Commun , 17
PUBMED: 42722693
DOI: doi:10.1038/s41467-026-77556-3
ISSN: 2041-1723