EMD-77329

Subtomogram averaging
24.5 Å
EMD-77329 Deposition: 27/05/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-77329

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Focused map of four central LRRK2 I2020T units in the microtubule-associated filament lattice formed in the presence of MLi-2

EMD-77329

Subtomogram averaging
24.5 Å
EMD-77329 Deposition: 27/05/2026
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: HEK293T cell expressing human LRRK2 I2020T treated with MLi-2

Deposition Authors: Basiashvili T, Villa E

In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association

Basiashvili T, Villa E
To Be Published
Grant Support: