EMD-77145

Single-particle
2.49 Å
EMD-77145
3D View Gallery
Deposition: 13/05/2026
Map released: 01/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-77145

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-13lu summary report (pdf.gz) Map-13lu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of human TRPV3-W521S Olmsted syndrome mutant in the closed state

EMD-77145

Single-particle
2.49 Å
EMD-77145
3D View Gallery
Deposition: 13/05/2026
Map released: 01/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Aequorea victoria
Sample: TRPV3 tetramer
Fitted models: 13lu

Deposition Authors: Nadezhdin KD, Khau J, Purohit R, Sobolevsky AI
Structural diversity of heat-sensing channel TRPV3 with Olmsted syndrome mutations.
Khau J, Purohit R, Nadezhdin KD, Talyzina IA, Sobolevsky AI
(2026) Nat Commun , 17
PUBMED: 42323291
DOI: doi:10.1038/s41467-026-74687-5
ISSN: 2041-1723