EMD-76833

Single-particle
3.0 Å
EMD-76833
3D View Gallery
Deposition: 21/04/2026
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76833

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12xm summary report (pdf.gz) Map-12xm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Candida albicans Chitin synthase 1 (CaChs1) intermediate state (DA-3), bound to UDP and diynyl arylamine (DA, aka RO-09-3143)

EMD-76833

Single-particle
3.0 Å
EMD-76833
3D View Gallery
Deposition: 21/04/2026
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Candida albicans
Sample: Candida albicans Chitin synthase 1 (CaChs1) intermediate state (DA-3), bound to UDP and diynyl arylamine (DA, aka RO-09-3143)
Fitted models: 12xm

Deposition Authors: Ren Z, Lee SY
Cryo-EM structures of Candida albicans chitin synthase Chs1 reveal a druggable translocation channel.
Ren Z, Chhetri A, Liu C, Guan Z, Offner S, Kozhanov D, Borgnia MJ, Im W, Yokoyama K, Lee SY
(2026) Nat Microbiol
PUBMED: 42744982
DOI: doi:10.1038/s41564-026-02485-2
ISSN: 2058-5276