EMD-76733

Single-particle
3.38 Å
EMD-76733
3D View Gallery
Deposition: 16/04/2026
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76733

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12sn summary report (pdf.gz) Map-12sn FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

SARS-CoV-2 RNA-dependent RNA polymerase in complex with 4'-FlA nucleotide analogue

EMD-76733

Single-particle
3.38 Å
EMD-76733
3D View Gallery
Deposition: 16/04/2026
Map released: 24/06/2026
Last modified: 24/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 RNA-dependent RNA polymerase in complex with 4'-FlA nucleotide analogue
Fitted models: 12sn

Deposition Authors: Park S, Gharpure A, Ward AB
Substrate and target selectivity of 4'-fluoroadenosine against viral and host polymerases.
Walker SM, Loutan AJ, Tchesnokov EP, Kocincova D, Gordon CJ, Escobedo RA, Jackson N, Vogel OA, Morsheimer K, Park S, Gharpure A, Urbano I, Heacock M, Cheng Z, Pathak K, Wolff KC, Huerta L, Bakowski MA, Riva L, Gupta AK, Yu C, Das K, Martinez-Sobrido L, Basler CF, Davey R, Wilson IA, Ward AB, Chanda S, Chatterjee AK, Gotte M
(2026) bioRxiv
PUBMED: 42244653
DOI: doi:10.64898/2026.05.22.727251
ISSN: 2692-8205