EMD-76659

Single-particle
3.1 Å
EMD-76659
3D View Gallery
Deposition: 14/04/2026
Map released: 13/05/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76659

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12pb summary report (pdf.gz) Map-12pb FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Single particle cryo-EM structure of human MTCH2 (hyperactive mutant K25E Y235A V238D)

EMD-76659

Single-particle
3.1 Å
EMD-76659
3D View Gallery
Deposition: 14/04/2026
Map released: 13/05/2026
Last modified: 08/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: MTCH2 hyperactive mutant K25E Y235A V238D complexed with UCP1 nanobody
Fitted models: 12pb

Deposition Authors: Luo Z , Stevens TA , Voorhees RM
Structural evolution of the MTCH family of mitochondrial insertases.
Stevens TA , Luo Z , Lee C , Hazu M , Galatis EG , Inglis AJ, Guna A , Voorhees RM
(2026) Sci Adv , 12 , eaeh2957 - eaeh2957
PUBMED: 42308315
DOI: doi:10.1126/sciadv.aeh2957
ISSN: 2375-2548