EMD-76384

Single-particle
2.99 Å
EMD-76384 Deposition: 31/03/2026
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76384

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12er summary report (pdf.gz) Map-12er FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of BCMA in complex with the BCMA-targeted Fab arm of teclistamab and the Fab fragment of an anti-lambda light chain antibody REGN15499

EMD-76384

Single-particle
2.99 Å
EMD-76384 Deposition: 31/03/2026
Map released: 12/08/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: BCMA extracellular domain in complex with the BCMA-targeted Fab arm of teclistamab and the Fab fragment of an anti-lambda light chain antibody REGN15499
Fitted models: 12er

Deposition Authors: Zhou Y, Franklin MC
DISTINCT EPITOPE ENGAGEMENT CONFERS DIFFERENTIAL ACTIVITY OF LINVOSELTAMAB VERSUS TECLISTAMAB ACROSS BCMA MUTATIONS.
PUBMED: 42509021
DOI: doi:10.1182/bloodadvances.2026020381
ISSN: 2473-9537
Grant Support: