EMD-76375

Single-particle
3.1 Å
EMD-76375
3D View Gallery
Deposition: 30/03/2026
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76375

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12ef summary report (pdf.gz) Map-12ef FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed with ppGpp (ePEC semiclosed + ppGpp)

EMD-76375

Single-particle
3.1 Å
EMD-76375
3D View Gallery
Deposition: 30/03/2026
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: Bacterial RNA polymerase elemental paused elongation complex
Fitted models: 12ef

Deposition Authors: Mueller AU, Darst SA, Landick R
ppGpp regulates transcription elongation via direct and indirect inputs to RNA polymerase pausing and nucleotide addition.
Mueller AU, Mooney RA, Engstrom MD, Bao Y, Wolfe MB, Sah B, Buscher J, Saba J, Liu J, Darst SA, Landick R
(2026) bioRxiv
PUBMED: 42182161
DOI: doi:10.64898/2026.05.13.724835
ISSN: 2692-8205