EMD-76264
Structure of mammalian Type 2 Inositol 1,4,5-trisphosphate receptor (IP3R2) in the presence of IP3/Ca2+/ATP
EMD-76264
Single-particle3.64 Å
Deposition: 23/03/2026Map released: 29/07/2026
Last modified: 09/09/2026
Sample Organism:
Mus musculus
Sample: Inositol 1,4,5-trisphosphate receptor type 2
Fitted models: 12ai
Deposition Authors: Serysheva II
,
Baker MR
,
Fan G
Sample: Inositol 1,4,5-trisphosphate receptor type 2
Fitted models: 12ai
Deposition Authors: Serysheva II
,
Baker MR
,
Fan G
Cryo-EM insights into isoform-specific properties of the IP 3 R2 channel.
Baker MR
,
Lin X
,
Fan G
,
Martinez-Chavez A,
Wagner LE,
Malik S,
Allison T
,
Bell B
,
Seryshev AB,
Cordero-Morales J
,
Baker ML,
Yule DI
,
Serysheva II
(2026) Nat Commun , 17
,
Lin X
,
Fan G
,
Martinez-Chavez A,
Wagner LE,
Malik S,
Allison T
,
Bell B
,
Seryshev AB,
Cordero-Morales J
,
Baker ML,
Yule DI
,
Serysheva II
(2026) Nat Commun , 17
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM153178 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM153178-01S1 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM072804 (United States)
- American Heart Association: 23CDA1048883 (United States)
- Welch Foundation: AU-2014-20220331 (United States)
- Welch Foundation: AU-2014-20250403 (United States)
