EMD-76261

Single-particle
3.48 Å
EMD-76261
3D View Gallery
Deposition: 23/03/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-76261

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-12ag summary report (pdf.gz) Map-12ag FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Spermine-blocked open-state cryo-EM structure of human TRPV6 channel in cNW30 nanodiscs

EMD-76261

Single-particle
3.48 Å
EMD-76261
3D View Gallery
Deposition: 23/03/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: spermine-blocked open-state homotetrameric human TRPV6
Fitted models: 12ag

Deposition Authors: Neuberger A, Sobolevsky AI
Open-channel block of human TRPV6 by polyamine spermine.
Neuberger A, Veretenenko II, Shalygin A, Trofimov YA, Gudermann T, Chubanov V, Efremov RG, Sobolevsky AI
(2026) Nat Commun , 17
PUBMED: 42204171
DOI: doi:10.1038/s41467-026-73653-5
ISSN: 2041-1723