EMD-76259
Structure of mammalian Type 2 Inositol 1,4,5-trisphosphate receptors (IP3R2) in the Apo-state (composite map)
EMD-76259
Single-particle3.2 Å
Deposition: 22/03/2026Map released: 29/07/2026
Last modified: 29/07/2026
Sample Organism:
Mus musculus
Sample: Inositol 1,4,5-trisphosphate receptor type 2
Deposition Authors: Serysheva II
,
Baker MR ,
Fan G
Sample: Inositol 1,4,5-trisphosphate receptor type 2
Deposition Authors: Serysheva II
,
Baker MR ,
Fan G
Cryo-EM insights into isoform-specific properties of the IP3R2 channel
Baker MR ,
Lin X,
Fan G ,
Martinez-Chavez A,
Wagner LE,
Malik S,
Allison T,
Bell B,
Seryshev AB,
Cordero-Morales J,
Baker ML,
Yule DI,
Serysheva II
(2026) Nat Commun
,
Lin X,
Fan G ,
Martinez-Chavez A,
Wagner LE,
Malik S,
Allison T,
Bell B,
Seryshev AB,
Cordero-Morales J,
Baker ML,
Yule DI,
Serysheva II
(2026) Nat Commun
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM153178 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R35GM153178-01S1 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM072804 (United States)
- American Heart Association: 23CDA1048883 (United States)
- Welch Foundation: AU-2014-20220331 (United States)
- Welch Foundation: AU-2014-20250403 (United States)