EMD-75822

Helical reconstruction
4.0 Å
EMD-75822
3D View Gallery
Deposition: 03/03/2026
Map released: 11/11/2026
Last modified: 11/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75822

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of a tau(297-407)-4D filament grown in potassium citrate buffer for 42 days (polymorph 1)

EMD-75822

Helical reconstruction
4.0 Å
EMD-75822
3D View Gallery
Deposition: 03/03/2026
Map released: 11/11/2026
Last modified: 11/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: tau(297-407) S396D S400D T403D S404D

Deposition Authors: Yan NL, Powell WC , Tse E, Melo AA, Southworth DR , Gestwicki JE
Cofactor-Free Tau Filaments Are Dynamic and Undergo Structural Evolution Driven by Thermodynamic Control.
Powell WC , Yan N, Tse E, Melo AA, Vasquez JA, Southworth DR , Gestwicki JE
(2026) J Am Chem Soc , 148 , 35386 - 35398
PUBMED: 42677560
DOI: doi:10.1021/jacs.6c04928
ISSN: 1520-5126
ASTM: JACSAT
Grant Support: