EMD-75737
Cryo-EM structure of pSTAT1 bound to importin alpha 5 (4:2 assembly)
EMD-75737
Single-particle3.6 Å
Deposition: 26/02/2026Map released: 04/11/2026
Last modified: 04/11/2026
Sample Organism:
Homo sapiens
Sample: This is a complex of domain-swapped dimer of pSTAT1:importin aplha 5 heterodimers.
Fitted models: 11jg
Deposition Authors: Kumar P
,
Bellis NF ,
Yang R ,
Vinkemeier U ,
Cingolani G
Sample: This is a complex of domain-swapped dimer of pSTAT1:importin aplha 5 heterodimers.
Fitted models: 11jg
Deposition Authors: Kumar P
,
Bellis NF ,
Yang R ,
Vinkemeier U ,
Cingolani G
Cytokine-induced nuclear translocation of STAT1 via a non-transferable NLS.
Kumar P ,
Cavey JR ,
Yang R ,
White O,
Begitt A,
He L,
Suinn SS ,
Bellis NF ,
Lokareddy RK ,
Vinkemeier U ,
Cingolani G
(2026) bioRxiv
,
Cavey JR ,
Yang R ,
White O,
Begitt A,
He L,
Suinn SS ,
Bellis NF ,
Lokareddy RK ,
Vinkemeier U ,
Cingolani G
(2026) bioRxiv
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI191107 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): GM140733 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): AI194663 (United States)