EMD-75506

Single-particle
7.33 Å
EMD-75506
3D View Gallery
Deposition: 11/02/2026
Map released: 24/06/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75506

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM map of Ascl1-E12a in complex with NRCAM nucleosome without scFv

EMD-75506

Single-particle
7.33 Å
EMD-75506
3D View Gallery
Deposition: 11/02/2026
Map released: 24/06/2026
Last modified: 22/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: 162bp NRCAM nucleosome in complex with Ascl1/E12a

Deposition Authors: Zhou BR, Bai Y
Distinct associations of pioneer factor Ascl1-E12a with nucleosomes drive changes in cell fate.
Zhou BR, Luzete-Monteiro E, Zhang J, Takenaka N, Tang HY, Fernandez Garcia M, Coradin M, Frederick M, Donahue G, Garcia B, Bai Y, Zaret KS
(2026) Mol Cell , 86 , 2458 - 2473.e13
PUBMED: 42285106
DOI: doi:10.1016/j.molcel.2026.05.020
ISSN: 1097-2765
ASTM: MOCEFL