EMD-75389

Single-particle
2.49 Å
EMD-75389
3D View Gallery
Deposition: 01/02/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75389
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 10qm summary report (pdf.gz) Map and 10qm FULL report (pdf.gz)
EMICSS annotations (xml)

E.coli 50S ribosomal subunit bound to compound 48a

EMD-75389

Single-particle
2.49 Å
EMD-75389
3D View Gallery
Deposition: 01/02/2026
Map released: 10/06/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli
Sample: 50S ribosomal subunit
Fitted models: 10qm

Deposition Authors: Raskar T, Lee I
Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome.
Lee IJ, Li Q, Raskar T, Pellegrino J, Ecker AK, Howard SY, Fraser JS, Seiple IB
(2026) Eur.J.Med.Chem. , 316 , 118947 - 118947
PUBMED: 42214237
DOI: doi:10.1016/j.ejmech.2026.118947
ISSN: 0223-5234
ASTM: EJMCA5