EMD-75274

Single-particle
3.94 Å
EMD-75274
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Deposition: 27/01/2026
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75274
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Heteromeric GluA1/A2 in the activated state, amino-terminal domain (ATD)

EMD-75274

Single-particle
3.94 Å
EMD-75274
3D View Gallery
Deposition: 27/01/2026
Map released: 08/04/2026
Last modified: 08/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Heteromeric GluA1A2 with positive allosteric modulator (R,R)-2b and agonist glutamate (Glu)

Deposition Authors: Yen LY , Newton TP , Gangwar SP , Sobolevsky AI
Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core.
Yen LY , Newton TP , Yelshanskaya MV, Aktolun M, Gangwar SP , Clausen RP, Kurnikova MG, Sobolevsky AI
(2026) Nat Commun
PUBMED: 41904128
DOI: doi:10.1038/s41467-026-71063-1
ISSN: 2041-1723