EMD-75048

Single-particle
3.11 Å
EMD-75048
3D View Gallery
Deposition: 09/01/2026
Map released: 06/05/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75048

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human Excitatory Amino Acid Transporter 3 in 300 mM potassium and 0.1 mM Cmpd 3e in the intermediate outward-facing (iOFS) state

EMD-75048

Single-particle
3.11 Å
EMD-75048
3D View Gallery
Deposition: 09/01/2026
Map released: 06/05/2026
Last modified: 10/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human excitatory amino acid transporter 3

Deposition Authors: Earsley A , Qiu B , Boudker O
Structure-guided optimization of SLC1A1/EAAT3-selective inhibitors targeting renal cancer metabolism.
Koochaki P, Qiu B , Coker JA, Earsley A , Wang NS, Romigh T, Goins CM, Salem C, Mi D, Days E, Bauer JA, Stauffer SR, Boudker O , Chakraborty AA
(2026) EMBO J , 45 , 3763 - 3787
PUBMED: 42020573
DOI: doi:10.1038/s44318-026-00776-2
ISSN: 1460-2075
ASTM: EMJODG
Grant Support: