EMD-75024

Single-particle
3.44 Å
EMD-75024
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Deposition: 08/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-75024
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 10ad summary report (pdf.gz) Map and 10ad FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human BK channel bound to the agonist NS1619

EMD-75024

Single-particle
3.44 Å
EMD-75024
3D View Gallery
Deposition: 08/01/2026
Map released: 04/02/2026
Last modified: 04/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: hBK NS1619 complex
Fitted models: 10ad

Deposition Authors: Gonzalez-Sanabria N, Contreras GF, Perozo E, Latorre R
The BK channel-NS1619 agonist complex reveals molecular insights into allosteric activation gating
Gonzalez-Sanabria N, Contreras GF, Rojas M, Duarte Y, Gonzalez-Nilo FD, Perozo E, Latorre R
(2026) PNAS , 123
DOI: doi:10.1073/pnas.2507707123
ISSN: 1091-6490
ASTM: PNASA6