EMD-74919

Single-particle
3.4 Å
EMD-74919
3D View Gallery
Deposition: 03/01/2026
Map released: 29/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74919

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zxc summary report (pdf.gz) Map-9zxc FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of AT118-R nanobody in complex with the angiotensin II type I receptor bound to losartan

EMD-74919

Single-particle
3.4 Å
EMD-74919
3D View Gallery
Deposition: 03/01/2026
Map released: 29/07/2026
Last modified: 12/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Homo sapiens
Sample: Structure of AT118-R Nanobody in Complex with the Angiotensin II Type I Receptor and Losartan
Fitted models: 9zxc

Deposition Authors: Skiba MA, Gilman MSA , Kruse AC
Activation of the angiotensin II type I receptor by a nonpeptide agonist.
Skiba MA, Liu J, Shen P , Kim J, Wren E, Gilman MSA , Staus D, McMahon C , Smith JS , Lefkowitz RJ , Kahne D , Wingler LM , Kruse AC
(2026) PNAS , 123 , e2602538123 - e2602538123
PUBMED: 42550893
DOI: doi:10.1073/pnas.2602538123
ISSN: 1091-6490
ASTM: PNASA6