EMD-74712

Single-particle
2.69 Å
EMD-74712
3D View Gallery
Deposition: 22/12/2025
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74712

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zsi summary report (pdf.gz) Map-9zsi FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Nucleosome with an SSB at SHL +5.3 in complex with human PARP2, HPF1, and Talazoparib, Class 4

EMD-74712

Single-particle
2.69 Å
EMD-74712
3D View Gallery
Deposition: 22/12/2025
Map released: 14/10/2026
Last modified: 14/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Drosophila melanogaster, synthetic construct, Mus musculus, Homo sapiens
Sample: Nucleosome with an SSB at SHL +5.3 in complex with human PARP2, HPF1, and Talazoparib, Class 4
Fitted models: 9zsi

Deposition Authors: Gregory-Lott E, Kim TH, Jayathilake C, Virk RK
Structural basis of PARP2 recognition of nucleosomal DNA breaks and inhibitor trapping.
Jayathilake C, Gregory-Lott ER, Virk RK, Koh GK, Cho E, Kim TH
(2026) Nucleic Acids Res , 54
PUBMED: 42831429
DOI: doi:10.1093/nar/gkag939
ISSN: 1362-4962
ASTM: NARHAD