EMD-74656
Cryo-EM structure of SHIV-elicited CI93-1365 Fab in complex with HIV Env trimer Q23-SCT27
EMD-74656
Single-particle2.9 Å
Deposition: 21/12/2025Map released: 03/06/2026
Last modified: 02/09/2026
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus
Sample: CI93-1365 Fab in complex with HIV envelope trimer
Fitted models: 9zrz
Deposition Authors: Roark RS, Shapiro LS, Kwong PD
,
Kwong PD
Sample: CI93-1365 Fab in complex with HIV envelope trimer
Fitted models: 9zrz
Deposition Authors: Roark RS, Shapiro LS, Kwong PD
,
Kwong PD
Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies.
Marchitto L ,
Wagh K,
Roark RS,
Coleon S,
Li H,
Skelly AN ,
Hogarty MP ,
Habib R ,
Ding W,
Ayyanathan K,
Liu W,
Sheng Z ,
Guo Y ,
Bal J,
Smith LM,
Sutherland LL,
Park Y ,
Connell AJ ,
Bibollet-Ruche F ,
Lewis E ,
Plante SJ,
Akeley MJ ,
Lora J ,
Zhao C,
Carey JW,
Martella CL,
Li Y ,
Campion MS,
Lituchy MG,
Osbaldeston RA ,
Gordon CG,
Albertus A,
Su J ,
Noguchi C ,
Tam YK ,
Barbosa C,
Liang B,
Amereh K,
Li X,
Walsh AA,
Irvine DJ ,
Andrabi R,
Edwards RJ,
Kreider EF,
Weissman D ,
Shapiro L ,
Kwong PD ,
Korber BT,
Haynes BF ,
Saunders KO ,
Hahn BH,
Shaw GM
(2026) Nature , 656 , 712 - 722
,
Wagh K,
Roark RS,
Coleon S,
Li H,
Skelly AN ,
Hogarty MP ,
Habib R ,
Ding W,
Ayyanathan K,
Liu W,
Sheng Z ,
Guo Y ,
Bal J,
Smith LM,
Sutherland LL,
Park Y ,
Connell AJ ,
Bibollet-Ruche F ,
Lewis E ,
Plante SJ,
Akeley MJ ,
Lora J ,
Zhao C,
Carey JW,
Martella CL,
Li Y ,
Campion MS,
Lituchy MG,
Osbaldeston RA ,
Gordon CG,
Albertus A,
Su J ,
Noguchi C ,
Tam YK ,
Barbosa C,
Liang B,
Amereh K,
Li X,
Walsh AA,
Irvine DJ ,
Andrabi R,
Edwards RJ,
Kreider EF,
Weissman D ,
Shapiro L ,
Kwong PD ,
Korber BT,
Haynes BF ,
Saunders KO ,
Hahn BH,
Shaw GM
(2026) Nature , 656 , 712 - 722
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