EMD-7463

Single-particle
4.7 Å
EMD-7463
3D View Gallery
Deposition: 11/02/2018
Map released: 14/03/2018
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-7463
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6ceb summary report (pdf.gz) Map and 6ceb FULL report (pdf.gz)
EMICSS annotations (xml)

Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry

EMD-7463

Single-particle
4.7 Å
EMD-7463
3D View Gallery
Deposition: 11/02/2018
Map released: 14/03/2018
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Name: Insulin Receptor Ectodomain in complex with two insulin molecules, C1 symmetry
Complex [5]
Name: Insulin Receptor Ectodomain in complex with two insulin molecules, C1 symmetry
Molecular weight
Experimental Theoretical Method
- 215 kDa -
Name: Insulin receptor
Natural source [1]
Organism: Homo sapiens
Complex Portal [1]
ID Name Overlap
CPX-26675 INSR, insulin receptor complex 1.00
Name: Insulin receptor subunit alpha
Natural source [1]
Organism: Homo sapiens
Complex Portal [1]
ID Name Overlap
CPX-26675 INSR, insulin receptor complex 1.00
Name: Insulin A chain
Natural source [1]
Organism: Homo sapiens
Complex Portal [1]
ID Name Overlap
CPX-943 Insulin complex 1.00
Name: Insulin B chain
Natural source [1]
Organism: Ovis aries
Protein [4]
LEVO
Name: Insulin receptor
EC number: 2.7.10.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 104 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Mus musculus - - -
LEVO
Name: Insulin receptor
EC number: 2.7.10.1
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 3 kDa -
Recombinant Expression
Organism Strain Cell Plasmid
Mus musculus - - -
LEVO
Name: Insulin A chain
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [2]

Molecular function:
hormone activity
Cellular location:
extracellular region
Natural source
Organism: Homo sapiens
Molecular weight
Experimental Theoretical Method
- 2 kDa -
LEVO
Name: Insulin B chain
Number of copies: 2
UniProtKB PDBe-KB AlphaFold DB
Domains
Gene Ontology [1]

Molecular function:
hormone activity
Natural source
Organism: Ovis aries
Molecular weight
Experimental Theoretical Method
- 3 kDa -
Ligand [1]
Name: 2-acetamido-2-deoxy-beta-D-glucopyranose
HET code: NAG
Number of copies: 4
ChEMBL ChEBI
Molecular weight
Experimental Theoretical Method
- 221 Da -