EMD-7460
Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
EMD-7460
Single-particle3.6 Å
Deposition: 08/02/2018
Map released: 16/05/2018
Last modified: 29/07/2020
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1
Sample: vFP20.01-BG505 DS-SOSIP-VRC03-PGT122
Fitted models: 6cdi
Deposition Authors: Acharya P, Carragher B, Potter CS, Kwong PD
Sample: vFP20.01-BG505 DS-SOSIP-VRC03-PGT122
Fitted models: 6cdi
Deposition Authors: Acharya P, Carragher B, Potter CS, Kwong PD
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.
Xu K,
Acharya P ,
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Sheng Z ,
Todd JP,
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Viox EG,
Wang Y,
Wei H,
Yang Y,
Zhou AF,
Chen R,
Yang L,
Scorpio DG,
McDermott AB ,
Shapiro L,
Carragher B,
Potter CS,
Mascola JR,
Kwong PD
(2018) Nat. Med. , 24 , 857 - 867
(2018) Nat. Med. , 24 , 857 - 867