EMD-74550

Single-particle
5.2 Å
EMD-74550
3D View Gallery
Deposition: 17/12/2025
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74550
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9zq7 summary report (pdf.gz) Map and 9zq7 FULL report (pdf.gz)
EMICSS annotations (xml)

Autoinhibited P-Rex2 Composite Map

EMD-74550

Single-particle
5.2 Å
EMD-74550
3D View Gallery
Deposition: 17/12/2025
Map released: 15/07/2026
Last modified: 15/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 (P-Rex2)
Fitted models: 9zq7

Deposition Authors: Anderson LK, Cash JN
The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1.
Anderson LK, Marde R, Muma G, Nayak V, Phan C, Li S, Cash JN
(2026) J Biol Chem , 302 , 113229 - 113229
PUBMED: 42248461
DOI: doi:10.1016/j.jbc.2026.113229
ISSN: 1083-351X
ASTM: JBCHA3