EMD-74549

Single-particle
6.4 Å
EMD-74549
3D View Gallery
Deposition: 17/12/2025
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74549
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Autoinhibited P-Rex2 Local Refinement of Whole Particle

EMD-74549

Single-particle
6.4 Å
EMD-74549
3D View Gallery
Deposition: 17/12/2025
Map released: 01/07/2026
Last modified: 01/07/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 (P-Rex2)

Deposition Authors: Anderson LK , Cash JN
The Rho guanine-nucleotide exchange factor P-Rex2 exhibits structural and regulatory features distinct from the related RhoGEF P-Rex1.
Anderson LK , Marde R, Muma G, Nayak V, Phan C, Li S, Cash JN
(2026) J Biol Chem , 113229 - 113229
PUBMED: 42248461
DOI: doi:10.1016/j.jbc.2026.113229
ISSN: 1083-351X
ASTM: JBCHA3