EMD-74457

Single-particle
3.36 Å
EMD-74457
3D View Gallery
Deposition: 14/12/2025
Map released: 21/10/2026
Last modified: 21/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74457

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9znu summary report (pdf.gz) Map-9znu FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of L9-yd19 in complex with Plasmodium falciparum circumsporozoite protein (PfCSP) Kenya2-3 strain

EMD-74457

Single-particle
3.36 Å
EMD-74457
3D View Gallery
Deposition: 14/12/2025
Map released: 21/10/2026
Last modified: 21/10/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: synthetic construct, Plasmodium falciparum (isolate 3D7), Plasmodium falciparum
Sample: PfCSP:L9-yd19
Fitted models: 9znu

Deposition Authors: Tripathi P , Kwong PD
Anti-malaria antibody engineering broadens recognition motifs and reveals new homotypic interactions that enhance protective breadth.
Chun J, Tripathi P , Flores-Garcia Y, Madan B, Lee GA, Fahad AS, Lei H , Teng IT, Hurlburt NK , Flynn BJ, Pancera M , Miura K , Zhou T , Idris AH , Zavala F , Seder RA , Kwong PD , DeKosky BJ
(2026) Nat Commun , 17
PUBMED: 42660882
DOI: doi:10.1038/s41467-026-75840-w
ISSN: 2041-1723