EMD-74330

Single-particle
6.35 Å
EMD-74330
3D View Gallery
Deposition: 05/12/2025
Map released: 22/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74330
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

SMO/PKA-C complex, mixed prior to grid preparation

EMD-74330

Single-particle
6.35 Å
EMD-74330
3D View Gallery
Deposition: 05/12/2025
Map released: 22/04/2026
Last modified: 22/04/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Bos taurus
Sample: SMO/PKA-C

Deposition Authors: Liu G , Myers BR
Structural Mechanism for Noncanonical GPCR Signaling in the Hedgehog Pathway
Steiner WP, Iverson N, Liu G , Venkatakrishnan V, Wu J, Stepniewski TM, Michaelson Z, Brockel JW, Zhu J-F, Bruystens JGH, Lee A, Nelson I, Bertinetti D, Arveseth CD, Tan G, Spaltenstein P, Xu J, Huttenhain R, Kay MS, Herberg FW, Cao E, Selent J, Anand GS, Dunbrack Jr RL, Taylor SS, Myers BR
(2026) Nat Struct Mol Biol
DOI: doi:10.1038/s41594-026-01800-z
ISSN: 1545-9985