EMD-74125

Single-particle
3.9 Å
EMD-74125
3D View Gallery
Deposition: 01/12/2025
Map released: 08/04/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74125

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Parus major TRPM8, fully-swapped state determined in the presence of menthol

EMD-74125

Single-particle
3.9 Å
EMD-74125
3D View Gallery
Deposition: 01/12/2025
Map released: 08/04/2026
Last modified: 27/05/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Parus major
Sample: Homotetrameric complex of Parus major TRPM8 determined in a cell-derived vesicles.

Deposition Authors: Choi KY , Lin X , Cheng Y , Julius D
Structural energetics of cold sensitivity.
Choi KY , Lin X , Cheng Y , Julius D
(2026) Nature , 653 , 962 - 970
PUBMED: 41882351
DOI: doi:10.1038/s41586-026-10276-2
ISSN: 1476-4687
ASTM: NATUAS