EMD-74121

Single-particle
3.1 Å
EMD-74121
3D View Gallery
Deposition: 30/11/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74121

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zev summary report (pdf.gz) Map-9zev FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Germline-like A3A bound to single-chain Titin-B2M-HLA*A01

EMD-74121

Single-particle
3.1 Å
EMD-74121
3D View Gallery
Deposition: 30/11/2025
Map released: 04/11/2026
Last modified: 04/11/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mammalia
Sample: TCR-peptide-MHC
Fitted models: 9zev

Deposition Authors: Wang N , Borowska MT , Jude KM , Garcia KC
MHC restriction is structurally encoded by the T cell receptor germline.
Wang N , Borowska MT , Jude KM , Chen X , Wang C , Xiang X , Liu LD , Ma R , Motiani A, Wilson SC , Liu W , Garcia KC
(2026) bioRxiv
PUBMED: 42856299
DOI: doi:10.64898/2026.09.24.754241
ISSN: 2692-8205
Grant Support: