EMD-74078

Single-particle
3.9 Å
EMD-74078
3D View Gallery
Deposition: 26/11/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74078

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zdy summary report (pdf.gz) Map-9zdy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Human TTR-C10A at pH 4

EMD-74078

Single-particle
3.9 Å
EMD-74078
3D View Gallery
Deposition: 26/11/2025
Map released: 16/09/2026
Last modified: 16/09/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TTR homotetramer
Fitted models: 9zdy

Deposition Authors: Schaefer JH , Lander GC
Transthyretin can denature by an alternative pathway.
Jager M, Schafer JH, Lander GC , Powers ET, Gruebele M, Kelly JW
(2026) PNAS , 123 , e2536532123 - e2536532123
PUBMED: 42709794
DOI: doi:10.1073/pnas.2536532123
ISSN: 1091-6490
ASTM: PNASA6