EMD-74045

Single-particle
2.5 Å
EMD-74045
3D View Gallery
Deposition: 24/11/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-74045

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9zcy summary report (pdf.gz) Map-9zcy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of apo-ATR-ATRIP

EMD-74045

Single-particle
2.5 Å
EMD-74045
3D View Gallery
Deposition: 24/11/2025
Map released: 05/08/2026
Last modified: 05/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: ATR-ATRIP
Fitted models: 9zcy

Deposition Authors: Li B , Pavletich NP
Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase.
Li B , Yaseen A, Pavletich NP
(2026) Nat Struct Mol Biol
PUBMED: 42493622
DOI: doi:10.1038/s41594-026-01844-1
ISSN: 1545-9985