EMD-73873

Single-particle
1.99 Å
EMD-73873
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Deposition: 16/11/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73873
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9z7a summary report (pdf.gz) Map and 9z7a FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of Secreted extracellular protein A (SepA) from Shigella flexneri complexed with the fragment antigen binding domain of monoclonal antibody 40

EMD-73873

Single-particle
1.99 Å
EMD-73873
3D View Gallery
Deposition: 16/11/2025
Map released: 03/06/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Shigella flexneri 2a str. 2457T, Homo sapiens
Sample: Binary complex of the recombinant SepA passenger domain with Fab 40
Fitted models: 9z7a

Deposition Authors: Buckley DP, Berndsen ZT

Human infection with enterotoxigenic E. coli elicits antibodies that broadly neutralize mucin-degrading proteases of pathogenic E. coli and Shigella
Buckley DP, Akhtar M, Thapa M, Schmitz A, Turner J, Vickers TJ, Khatoon N, Kaisar H, Coggin JA, Ganguli D, Sheikh A, Laird RM, Poly F, Porter CK, Ruiz-Perez F, Miller MJ, Bhuiyan TR, Qadri F, Trillo-Muyo S, Dolan B, van der Post S, Ellebedy A, Berndsen ZT, Fleckenstein JM
To Be Published