EMD-73868
Constituent EM map: local refinement of putative MUC2 binding domain of rEatAp and Fab G12 from best Fab-containing 2D classes
EMD-73868
Single-particle3.69 Å
Deposition: 16/11/2025Map released: 10/06/2026
Last modified: 01/07/2026
Sample Organism:
Escherichia coli,
Homo sapiens
Sample: Binary complex of the recombinant EatA passenger domain with Fab G12
Deposition Authors: Buckley DP
,
Berndsen ZT
Sample: Binary complex of the recombinant EatA passenger domain with Fab G12
Deposition Authors: Buckley DP
,
Berndsen ZT
Human enterotoxigenic Escherichia coli (ETEC) infections elicit antibodies that broadly neutralize mucinases of pathogenic Escherichia coli and Shigella.
Buckley DP ,
Akhtar M,
Thapa M,
Schmitz A,
Turner J,
Vickers TJ,
Khatoon N,
Kaisar MH,
Coggin JA,
Ganguli D,
Sheikh A,
Laird RM,
Poly F,
Porter CK,
Ruiz-Perez F,
Miller MJ,
Chowdhury F,
Bhuiyan TR,
Qadri F,
Trillo-Muyo S,
Dolan B,
van der Post S,
Ellebedy A,
Berndsen ZT ,
Fleckenstein JM
(2026) PNAS , 123 , e2614012123 - e2614012123
,
Akhtar M,
Thapa M,
Schmitz A,
Turner J,
Vickers TJ,
Khatoon N,
Kaisar MH,
Coggin JA,
Ganguli D,
Sheikh A,
Laird RM,
Poly F,
Porter CK,
Ruiz-Perez F,
Miller MJ,
Chowdhury F,
Bhuiyan TR,
Qadri F,
Trillo-Muyo S,
Dolan B,
van der Post S,
Ellebedy A,
Berndsen ZT ,
Fleckenstein JM
(2026) PNAS , 123 , e2614012123 - e2614012123
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI089894 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI126887 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): T32AI007172 (United States)
- Department of Veterans Affairs (VA, United States): 5I01BX001469-05 (United States)