EMD-73803

Single-particle
2.64 Å
EMD-73803
3D View Gallery
Deposition: 10/11/2025
Map released: 10/06/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73803

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9z4h summary report (pdf.gz) Map-9z4h FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of human Wntless in complex with Wnt5a at 1:1 stoichiometry

EMD-73803

Single-particle
2.64 Å
EMD-73803
3D View Gallery
Deposition: 10/11/2025
Map released: 10/06/2026
Last modified: 19/08/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human Wntless in complex with Wnt5a at 1:1 stoichiometry
Fitted models: 9z4h

Deposition Authors: Ge Y , de Almeida Magalhaes T , Wu H, Wang Z , Salic A, Jiang J , Huang P
Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens.
Ge Y , de Almeida Magalhaes T , Wu H, van den Boomen DJH , Nguyen TU, Dou T , Yadav GP , Lee S , Wang Z , Lemoff A , Luo X, Menon SS, Zhang M, Wang J , Jin Z, Jiang J , Salic A, Huang P
(2026) Nat Commun , 17
PUBMED: 42321207
DOI: doi:10.1038/s41467-026-74521-y
ISSN: 2041-1723