EMD-73787

Single-particle
3.3 Å
EMD-73787
3D View Gallery
Deposition: 07/11/2025
Map released: 13/05/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-73787

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9z3k summary report (pdf.gz) Map-9z3k FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map)

SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)

EMD-73787

Single-particle
3.3 Å
EMD-73787
3D View Gallery
Deposition: 07/11/2025
Map released: 13/05/2026
Last modified: 03/06/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Severe acute respiratory syndrome coronavirus 2
Sample: SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Fitted models: 9z3k

Deposition Authors: McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D
TMPRSS2-mediated coronavirus spike activation and inhibition.
McCallum M, Case JB, Brown JT, Park YJ, Lee J, Sutherland E, Aggarwal A, Gibson C, Lempp FA, Stewart C, Tortorici MA, Sanapala S, Low JS, Asarnow D, Bohan D, Dellota Jr E, Merz B, Chawla B, Kar S, Lanzavecchia A, Sallusto F, Riley NM, Turville S, Purcell L, Diamond MS, Veesler D
(2026) Nat Struct Mol Biol , 33 , 810 - 823
PUBMED: 42050172
DOI: doi:10.1038/s41594-026-01801-y
ISSN: 1545-9985
Grant Support: